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L-Buthionine-sulfoximine; L-Buthionine (S,R)-sulfoximine

Chinese name 丁硫氨酸-亚砜亚胺
Chinese synonyms 丁硫氨酸-亚砜亚胺
English name L-Buthionine-sulfoximine; L-Buthionine (S,R)-sulfoximine
English synonyms L-Buthionine-sulfoximine; L-Buthionine (S,R)-sulfoximine
[U-Chemo Code]: PY828
CAS: 83730-53-4
Molecular Formular C8H18N2O3S
Molecular Weight 222.31
Molecular Structure
Density 1.3±0.1 g/cm3
Appearance White Powder
Specification

98%min

Optical Rotation (c=1, HCl):+31°~+35°

Moisture: 0.5%max

Packing According request
Storage Sealed, in a cool, dry warehouse.
Application It is a cell-permeable, potent, fast-acting, irreversible inhibitor of G-glutamylcysteine γ synthetase that reduces intracellular glutathione levels with IC50s of 1.9 μM, 8.6 μM, and 29 μM for melanoma and breast ovarian cancer specimens, respectively.
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